The article is reproduced from:
Text | Professor Ye Zhangying of Zhejiang University "Electrolysis Water Technology Channel" Luo Haixin
Editor | "Electrolysis Water Technology Channel" Pei Luowei
In recent years, the breeding industry has entered a period of rapid development, but due to the intensive scale and high-density breeding of farms, the pathogens in farms have become increasingly complex, and these pathogens can cause epidemics under appropriate conditions, such as swine fever, foot-and-mouth disease, blue ear disease, porcine circovirus, avian influenza, high fever, etc. The faster the spread of pathogens, once an infectious disease breaks out, it is often too late to take measures, which will cause serious economic losses.
Disinfection is an important part of comprehensive disease prevention. Through scientific, reasonable and effective disinfection, cutting off the transmission routes of infectious diseases and reducing the number of pathogenic microorganisms in farms and poultry houses, the occurrence of infectious diseases can be reduced or avoided to a certain extent.
The application scope of acidic electrolyzed water/hypochlorous acid water is gradually expanding over time. Today we will briefly introduce the killing effect of acidic electrolyzed water/hypochlorous acid water on viruses that animals are susceptible to...
Part.1 Foot and mouth disease virus (FMDV)
Foot and mouth disease virus is an RNA virus that can cause foot and mouth disease. Foot and mouth disease is an acute, febrile, highly contagious disease shared by major livestock such as pigs, cattle, and sheep and other domestic and wild even-toed ungulates, with more than 70 susceptible animals. It can cause acute fever symptoms, vesicular rashes on the oral mucosa, hooves, and breast skin, and a high mortality rate in young animals. The disease has many transmission routes and a fast speed. It has repeatedly broken out worldwide, causing huge political and economic losses.
Vuong N. BUI et al. from Hokkaido Agricultural University in Japan studied the killing effect of acidic electrolyzed water on foot and mouth disease virus. The results showed that the treatment of foot-and-mouth disease virus suspension with acidic electrolyzed water (pH 2.6, ORP between 1109 and 1112 mV) in a ratio of 9:1 for 2 minutes can effectively kill the virus, reducing the number of viruses with RNA activity from 106 to less than 102, and the virus inactivation rate is >99.99%.
References: Bui VN, Nguyen KV, Pham NT, et al. Potential of electrolyzed water for disinfection of foot-and-mouth disease virus[J]. Journal of Veterinary Medical Science, 2017, 79(4):726-729.
Part.2 Avian influenza virus (AIV)
Avian influenza (Bird Flu or Avian Influenza) is the abbreviation of avian influenza, which is an acute infectious disease caused by a subtype of influenza A virus (also known as avian influenza virus). The morbidity and mortality of avian influenza vary greatly. When infected with highly pathogenic avian viruses, the morbidity and mortality can reach 100%.
The disease can be transmitted through multiple pathways such as the digestive tract, respiratory tract, skin lesions and conjunctiva of the eye. The movement of people and vehicles between regions is an important way to spread the disease.
Highly pathogenic avian influenza is an acute, febrile, highly contagious disease of chickens caused by highly pathogenic avian influenza virus subtypes. It is classified as a notifiable disease by the World Organization for Animal Health and is listed as a Class I infectious disease in the "List of Animal Quarantine Diseases Entering the People's Republic of China".
So far, the avian influenza virus subtypes that can directly infect humans are: H5N1, H7N1, H7N2, H7N3, H7N7, H9N2 and H7N9 subtypes. Among them, the highly pathogenic H5N1 subtype and the new avian influenza H7N9 subtype first discovered in humans in March 2013 are particularly noteworthy, not only causing human casualties, but also severely damaging the poultry farming industry.
Shio Tamaki et al. from Hokkaido University of Agriculture in Japan studied the killing effect of neutral electrolyzed water on avian influenza virus. They used neutral electrolyzed water (effective chlorine concentration ≥ 43ppm, pH between 6.4 and 7.4) and mixed it with highly pathogenic avian influenza (H5N1) virus and low pathogenic avian influenza (H9N2) virus in a ratio of 9:1 and treated it for 1 minute. Under this condition, neutral electrolyzed water can have a good killing effect on the virus, the number of active viruses has decreased by more than 5 logarithms, and the inactivation rate is >99.999%.
References: Tamaki S, Bui VN, Ngo LH, et al. Virucidal effect of acidic electrolyzed water and neutral electrolyzed water on avian influenza viruses[J]. Archives of Virology, 2014, 159(3):405-412.
Part.3 African Swine Fever (ASF)
African swine fever (ASF) is an acute, severe, and highly contagious disease caused by the African swine fever virus (ASFV) infecting domestic pigs and wild boars. It is listed as a notifiable animal disease by the World Organization for Animal Health (OIE), and China also lists it as a Class I animal epidemic that needs to be prevented.According to official data, as of the end of August 2019, a total of 147 African swine fever outbreaks were reported in 31 provinces, cities, and districts in China, with 19,355 pigs infected, 13,385 pigs dead, and 1.1276 million pigs killed or culled.
Chae Hong RHEE et al. from the Korea Animal and Plant Inspection and Quarantine Service published their latest research in the world-renowned veterinary journal "The Journal of Veterinary Medical Science": The killing effect of acidic electrolyzed water on African swine fever virus and avian influenza virus!
The researchers used acidic electrolyzed water with different effective chlorine concentrations (FCC) under different organic matter concentration conditions to test the effect of acidic electrolyzed water on reducing the titer of African swine fever virus (ASFV). The results are as follows:
Under low-level organic pollution conditions, AEW with FCC ≥ 40ppm is effective against African swine fever virus; under high-level organic pollution conditions, AEW with FCC ≥ 80ppm is effective against African swine fever virus.
References: Chae Hong RHEE, Soohee KIM, Young Eun KANG, Bokhee HAN, Sang-Ji SEO, Young Wook KIM, Moon HER, Wooseog JEONG.Virucidal efficacy of acidic electrolyzed water (AEW) against African swine fever virus and avian influenza virus:Virology [J].The Journal of Veterinary Medical ScienceVolume 83, Issue 2. 2021. PP201-207.
Part.4 Porcine reproductive and respiratory syndrome virus (PRRSV)
Porcine reproductive and respiratory syndrome virus (PRRSV) is a highly contagious disease of pigs caused by porcine reproductive and respiratory syndrome virus (PRRSV). It causes an acute, highly contagious viral infectious disease characterized by reproductive disorders and respiratory symptoms in pigs, which can cause reproductive disorders, breathing difficulties, blue and purple ears, and other infectious diseases in piglets, which seriously affects the pig industry.
The disease spreads quickly, especially in technologically advanced and economically developed countries, because of the dense and frequent movement of pigs, it is more likely to cause an epidemic. After a severe epidemic period, the disease is often endemic, which has long-term harm to pig production and caused huge economic losses to the pig industry.
Hao Xiaoxia et al. studied the killing effect of neutral electrolyzed water on porcine blue ear virus. The results showed that neutral electrolyzed water has a good killing effect on porcine blue ear virus, and the killing effect increases with the increase of effective chlorine concentration and treatment time. When the effective chlorine concentration of neutral electrolyzed water is greater than or equal to 50 mg/l and the treatment time is 10 min, the porcine reproductive and respiratory syndrome virus (PRRSV) with a TCID50 of 106.0/0.1 ml can be completely killed, with a killing rate of 100%.
References: Hao Xiaoxia, Shen Zhiqiang, Wang Jinliang, et al. Study on the inhibitory effect of neutral electrolyzed water on porcine reproductive and respiratory syndrome virus in vitro [C]// Commemorating the 30th anniversary of the founding of the Chinese Society of Agricultural Engineering and the annual academic conference of the Chinese Society of Agricultural Engineering. 2009.
Part.5 Pseudorabies virus (PRV)
Pseudorabies virus can cause fever, itching (except pigs) and encephalomyelitis in a variety of livestock and wild animals such as cattle, sheep, pigs, dogs and cats, and can cause acute infectious diseases in pigs. It is easy to cause abortion and stillbirth in pregnant sows, infertility in boars, mass death of newborn piglets, breathing difficulties and growth stagnation in fattening pigs, etc. It is one of the major infectious diseases that endanger the global pig industry.
Pseudorabies is highly contagious. In most cases, the disease is transmitted through nose-to-nose contact. Since pseudorabies is present in large quantities in the nasal cavity and oral area, nose-to-nose contact is the most common type of transmission.
The researchers used different concentrations of slightly acidic electrolyzed water (ACC is 50ppm, 70ppm) and pseudorabies virus suspension with a virus titer of 5.93 log10 TCID50/mL in a 9:1 ratio for 10 minutes. This treatment can effectively kill pseudorabies virus, and the virus inactivation amount reaches 5.93 orders of magnitude, with an inactivation rate of 100%.
References: Xiaoxia Hao; Zhiqiang Shen; Jinliang Wang; Qiang Zhang; Baoming Li; Chaoyuan Wang; Wei Cao. In vitro inactivation of porcine reproductive and respiratory syndrome virus and pseudorabies virus by slightly acidic electrolyzed water [J]. The Veterinary JournalVolume 197, Issue 2. 2013. PP 297-301
Chlory hypochlorous acid generators use electrolysis technology to generate high-purity hypochlorous acid (HOCl), a powerful disinfectant that can quickly kill a variety of animal viruses, including but not limited to:
- Avian influenza virus
- Classical Swine Fever Virus
- Foot-and-mouth disease virus
- Canine Parvovirus
- Feline panleukopenia virus
Hypochlorous acid has a broad-spectrum killing effect on viruses, bacteria and fungi, and can effectively block the virus transmission chain.
After disinfection, hypochlorous acid will naturally decompose into water and trace salts, which will not harm animals, the environment or operators. Compared with traditional chemical disinfectants, CHLORY hypochlorous acid generator is safer, more environmentally friendly and suitable for long-term use. Equipped with an intelligent control system, users can adjust the concentration of hypochlorous acid according to their needs, and the operation is simple and convenient. The equipment operates stably and can continuously provide high-concentration hypochlorous acid solution to meet large-scale disinfection needs.
Compared with traditional disinfection methods, the Chlory hypochlorous acid generator can significantly reduce disinfection costs. The equipment has lower salt consumption and electricity consumption, and has significant economic benefits in the long term use.
Chlory's hypochlorous acid generator is an ideal choice for dealing with animal virus infections due to its high efficiency, safety and environmental protection. Whether it is a large-scale farm or a small pet hospital, this equipment can provide reliable disinfection solutions, assist in animal health management, and ensure the sustainable development of the breeding industry.
For more information about Chlory and hypochlorous acid generators, visit www.chlory.com or contact info@chlory.com